cdr3

Alignment-free graph models of TCR and BCR repertoires built from Lempel-Ziv and FlashBack string decompositions. Compute sequence generation probability (Pgen) and repertoire diversity, and generate new sequences. Python with a C core.

Identification and quantification of Seq-Well TCR transcripts and their recovered CDR3 sequences.

A zero-dependency C++ wrapper for NCBI IgBLAST. Embeds IMGT databases and binaries into a single executable for standalone V(D)J assignment and enriched AIRR-formatted outputs.

Анализ последовательностей CDR3 антител

Probability model for biological sequences such as TCRβ CDR3s, learned from sequences alone with optional abundances: sequence probabilities, sequencing depth, publicness and repertoire comparison, summed over every combinatorially possible sequence without enumeration or simulation.